Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691953 | 0.87 | CTSB (0.48) | MEN1KMT2ASMN1; SMN2UTS2RALDH1A1 | |
| SCHEMBL5308017 | 0.85 | MEN1 (0.58) | MEN1KMT2AUTS2RALDH1A1POLB | |
| SCHEMBL3989762 | 0.85 | SUCNR1 (0.56) | UTS2R | |
| SCHEMBL5693091 | 0.83 | UTS2R (0.47) | MEN1KMT2ASMN1; SMN2UTS2R | |
| SCHEMBL5691904 | 0.83 | MMP12 (0.47) | MEN1KMT2AALDH1A1POLBPDE2A | |
| SCHEMBL3994922 | 0.80 | CTSA (0.56) | KMT2ASMN1; SMN2UTS2RALDH1A1 | |
| SCHEMBL5926435 | 0.76 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5927088 | 0.75 | TACR3 (0.51) | MEN1KMT2AALDH1A1POLBPDE2A | |
| SCHEMBL5927078 | 0.74 | SUCNR1 (0.56) | UTS2R | |
| SCHEMBL5926273 | 0.73 | POLB (0.46) | MEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660439-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Transtech Pharma, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014533-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |