Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 12/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.45 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691953 | 0.85 | CTSB (0.48) | UTS2RMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5691904 | 0.84 | MMP12 (0.47) | MEN1KMT2A | |
| SCHEMBL5692537 | 0.83 | MEN1 (0.49) | UTS2RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3994930 | 0.82 | CTSA (0.57) | UTS2RSUCNR1DCAF1 | |
| SCHEMBL5308017 | 0.81 | MEN1 (0.58) | UTS2RMEN1KMT2A | |
| SCHEMBL3994922 | 0.79 | CTSA (0.56) | UTS2RSUCNR1KMT2ASMN1; SMN2 | |
| SCHEMBL4831636 | 0.74 | DCAF1 (0.51) | UTS2RDCAF1MEN1LMNAKMT2A | |
| SCHEMBL5927170 | 0.74 | UTS2R (0.52) | UTS2RSUCNR1DCAF1 | |
| SCHEMBL5927034 | 0.73 | DCAF1 (0.52) | SUCNR1DCAF1MEN1KMT2A | |
| SCHEMBL3992014 | 0.73 | SERPINE1 (0.50) | UTS2RSUCNR1DCAF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660439-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Transtech Pharma, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014533-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |