Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570488 | 0.91 | NPC1 (0.50) | SNCATDP1PKMNPC1RAB9A | |
| SCHEMBL570416 | 0.87 | ALDH1A1 (0.37) | TDP1PKMNPC1RAB9AALDH1A1 | |
| SCHEMBL569245 | 0.84 | KMT2A (0.41) | TDP1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL569408 | 0.83 | MAPT (0.42) | TDP1ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL14955715 | 0.72 | ALDH1A1 (0.45) | NAMPTTDP1ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL569329 | 0.72 | MAPK8 (0.42) | MAPK8NAMPTTDP1ALDH1A1HSD17B10 | |
| SCHEMBL569678 | 0.71 | HCAR2 (0.61) | TDP1PKMMEN1KMT2APOLB | |
| SCHEMBL569756 | 0.68 | DRD3 (0.54) | TDP1ALDH1A1HSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL14159023 | 0.66 | CYP1A2 (0.63) | MAPK8NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL569471 | 0.64 | RET (0.44) | MAPK8TDP1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |