Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569408 | 0.92 | MAPT (0.42) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL570416 | 0.88 | ALDH1A1 (0.37) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL569756 | 0.85 | DRD3 (0.54) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL569330 | 0.84 | MAPK8 (0.42) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL569786 | 0.84 | HCAR2 (0.48) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL569400 | 0.83 | HTT (0.38) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL569396 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL570488 | 0.83 | NPC1 (0.50) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL569928 | 0.81 | LRRK2 (0.38) | KMT2AMEN1KDM4EMAPTHSD17B10 | |
| SCHEMBL569321 | 0.79 | MEN1 (0.68) | KMT2AMEN1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |