Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618052 | 0.80 | MAPT (0.53) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL11665015 | 0.80 | CES2 (0.52) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL22198795 | 0.77 | CES2 (0.48) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL6003192 | 0.77 | MAPT (0.59) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL546672 | 0.77 | F3 (0.59) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL28480552 | 0.77 | PRSS1 (0.55) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL13169175 | 0.75 | CA1 (0.60) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL6659781 | 0.74 | CA1 (0.65) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL31119870 | 0.74 | HDAC3 (0.61) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL30446001 | 0.74 | SMN1; SMN2 (0.57) | CA1CA2CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283898-B1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS | DSM IP ASSETS BV (NL) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005095629-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS BY MEANS OF AZEOTROPICALLY DRIED ENZYME COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2005-10-13 | — | — | WO | disclosed |
| WO-2005014509-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS | DSM IP ASSETS B.V. (NL) | 2005-02-17 | — | — | WO | disclosed |
| US-6841691-B2 | Process for the preparation of enantiomerically enriched esters and alcohols | DSM N.V. (NL) | 2005-01-11 | — | — | US | disclosed |
| US-20040077059-A1 | Process for the preparation of enantiomerically enriched esters and alcohols | DSM IP ASSETS B.V. (NL) | 2004-04-22 | — | — | US | disclosed |
| EP-1283898-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS | DSM N.V. (NL) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001090396-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS | DSM N.V. (NL) | 2001-11-29 | — | — | WO | disclosed |