SCHEMBL546672

SCHEMBL546672

C=CC(=O)c1ccc(OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 1/20 0.59
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
MAPT P10636 4/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 1/20 0.58
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
ALDH5A1 P51649 1/20 0.57
ABAT P80404 1/20 0.57
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
PARP1 P09874 1/20 0.55
PARP10 Q53GL7 1/20 0.55
PARP2 Q9UGN5 1/20 0.55
PARP4 Q9UKK3 1/20 0.55
TGM2 P21980 1/20 0.55
MAOB P27338 2/20 0.54
PKM P14618 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL14911004 0.88 ALDH5A1 (0.59) F3CES2CES1MAPTALDH1A1
SCHEMBL7000262 0.83 F3 (0.75) F3CES2CES1MAPTALDH1A1
SCHEMBL7000261 0.83 F3 (0.75) F3CES2CES1MAPTALDH1A1
SCHEMBL4256312 0.82 ALDH5A1 (0.80) F3MAPTALDH1A1HPGDALDH5A1
SCHEMBL6260774 0.81 F3 (0.62) F3CES2CES1MAPTALDH1A1
SCHEMBL1641142 0.81 CES2 (0.61) F3CES2CES1MAPTALDH1A1
SCHEMBL28111426 0.81 CES2 (0.61) F3CES2CES1MAPTALDH1A1
SCHEMBL31119870 0.80 HDAC3 (0.61) CES2CES1MAPTALDH1A1CA1
SCHEMBL14903558 0.80 ELANE (0.56) MAPTALDH1A1HPGDALDH5A1ABAT
SCHEMBL19309804 0.79 F3 (0.59) F3CES2CES1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116693-B Method for preparing sofosbuvir by combining 3, 3-diaryl acrolein and Grignard reagent 江苏科本药业有限公司 2021-04-27 CN claimed
CN-111233645-A Method for preparing tri-substituted cyclopentene by MBH/Wittig domino reaction of vinylon insertion 浙江大学 2020-06-05 CN claimed
CN-111116693-A Method for preparing sofosbuvir by combining 3, 3-diaryl acrolein and Grignard reagent 江苏科本药业有限公司 2020-05-08 CN claimed
WO-2015015511-A1 NOVEL METAL FREE PROCESS FOR ALLYLIC OXIDATION COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-02-05 WO claimed
US-7875285-B1 n acrylic ester polymer including a drug having anovercoating of a different acrylic ester polymer having a glass transition temperature of 35-50 degrees C. to control elution of the drug; temperature change morphology of drug polymer to change and increase release; thrombolytic agents; restenosis ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-01-25 US claimed
US-7105274-B2 Photoluminescent ethylene sensors WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-09-12 US claimed
US-20250376441-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT UNIV YONSEI IACF (KR) 2025-12-11 US disclosed
EP-3656756-B1 PROCESS FOR THE DIRECT ALPHA-METHYLENATION OF KETONES SPECIALTY OPERATIONS FRANCE (FR) 2025-12-03 EP disclosed
CN-116143718-B Anti-hepatitis B activity (E) - (3-phenyl isoxazole-5-) -methylene acetophenone oxime ether derivatives 广西大学 2024-12-06 CN disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
CN-113166027-B Direct alpha-methylation of ketones 罗地亚经营管理公司 2024-10-25 CN disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
CN-112004805-B Process for producing 5, 5-disubstituted-4, 5-dihydroisoxazoles 组合化学工业株式会社 2024-06-14 CN disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0543861-A1 IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-06-02 EP disclosed
WO-1992003422-A1 BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-03-05 WO disclosed
EP-0073456-B1 TETRAAZAANNULENE COBALT COMPLEX COMPOUNDS AND METHOD FOR PREPARATION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-11-27 EP disclosed
EP-0004624-B1 CHROMANON DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICINES AND GROWTH-PROMOTING AGENTS BAYER AG (DE) 1982-02-24 EP disclosed
US-4261988-A ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY BAYER AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed
EP-0004624-A2 Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents BAYER AG (DE) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250376441-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT PRKAA1, PRKAA2, PRKAG1 F3 3918/4885CES2 2668/4885CES1 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.