Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TCF4 | P15884 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618052 | 0.78 | MAPT (0.53) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11665015 | 0.78 | CES2 (0.52) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5693740 | 0.77 | CA1 (0.54) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11139517 | 0.76 | MAPT (0.59) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6003198 | 0.75 | MAPT (0.53) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22198795 | 0.75 | CES2 (0.48) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL546672 | 0.75 | F3 (0.59) | MAPTHPGDALDH1A1CYP2C19CA1 | |
| SCHEMBL28480552 | 0.75 | PRSS1 (0.55) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17513783 | 0.75 | HPGD (0.59) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| Chlorotrianisene SCHEMBL8225 | 0.74 | HPGD (1.00) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |