Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665015 | 0.82 | CES2 (0.52) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL5693740 | 0.80 | CA1 (0.54) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL3622034 | 0.80 | MAPT (0.57) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL546672 | 0.78 | F3 (0.59) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL22198795 | 0.78 | CES2 (0.48) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL6003192 | 0.78 | MAPT (0.59) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL28480552 | 0.78 | PRSS1 (0.55) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL5378414 | 0.78 | MAPT (0.59) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL3277627 | 0.78 | MAPT (0.59) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL718001 | 0.78 | ELANE (0.55) | MAPTALDH1A1KDM4EPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467661-B | Functionalized styrene thermoplastic elastomer and preparation method thereof | 大连理工大学 | 2020-06-16 | — | — | CN | claimed |
| CN-109467661-A | Functionalization styrene analog thermoplastic elastomer and preparation method thereof | 大连理工大学 | 2019-03-15 | — | — | CN | claimed |
| CN-109608420-B | Method for synthesizing functionalized 1,3-butadiene based on biomass chemicals | 中国科学院长春应用化学研究所 | 2023-02-28 | — | — | CN | disclosed |
| CN-111499857-B | Conjugated diene and epoxy compound block copolymer and preparation method thereof | 长春工业大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-111499857-A | Conjugated diene and epoxy compound block copolymer and preparation method thereof | 长春工业大学 | 2020-08-07 | — | — | CN | disclosed |
| EP-3444126-B1 | METHOD OF MAKING A FUNCTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-3444125-B1 | FUNCTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER (US) | 2020-08-05 | — | — | EP | disclosed |
| CN-109467661-B | Functionalized styrene thermoplastic elastomer and preparation method thereof | 大连理工大学 | 2020-06-16 | — | — | CN | disclosed |
| CN-106749910-B | A kind of 2,3- dimethyl -1,3- butadienyl block copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2019-06-04 | — | — | CN | disclosed |
| CN-109608420-A | A method of functionalization 1,3- butadiene is synthesized based on biomass chemicals | 中国科学院长春应用化学研究所 | 2019-04-12 | — | — | CN | disclosed |
| CN-109467661-A | Functionalization styrene analog thermoplastic elastomer and preparation method thereof | 大连理工大学 | 2019-03-15 | — | — | CN | disclosed |
| US-20190055334-A1 | METHOD OF MAKING A FUNCTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER COMPANY, THE | 2019-02-21 | — | — | US | disclosed |
| US-20190055335-A1 | FUNCTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER COMPANY, THE | 2019-02-21 | — | — | US | disclosed |
| EP-3444125-A1 | FUNCTIONALIZED ELASTOMER | The Goodyear Tire & Rubber Company (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-3444126-A1 | METHOD OF MAKING A FUNCTIONALIZED ELASTOMER | The Goodyear Tire & Rubber Company (US) | 2019-02-20 | — | — | EP | disclosed |
| CN-106749910-A | A kind of butadienyl block copolymer of 2,3 dimethyl 1,3 and preparation method thereof | 中国科学院长春应用化学研究所 | 2017-05-31 | — | — | CN | disclosed |
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190055334-A1 | METHOD OF MAKING A FUNCTIONALIZED ELASTOMER | CHRM1, CHRM2, F12 | MAPT 3368/4885CES2 605/4885CES1 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.