Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686819 | 0.79 | ATM (0.36) | NPC1RAB9A | |
| SCHEMBL7171824 | 0.75 | ACHE (0.41) | TDP1ACHEGAANPSR1ALDH1A1 | |
| SCHEMBL301896 | 0.69 | ACHE (0.50) | TSHRTDP1ACHEALDH1A1 | |
| SCHEMBL1538600 | 0.69 | ACHE (0.50) | TSHRTDP1ACHEALDH1A1 | |
| SCHEMBL297883 | 0.69 | ACHE (0.50) | TSHRTDP1ACHEALDH1A1 | |
| P-Xylene SCHEMBL11553864 | 0.67 | ACHE (0.80) | TSHRTDP1ACHEGAAALDH1A1 | |
| SCHEMBL5034146 | 0.67 | ACHE (0.47) | TSHRTDP1ACHENPC1ALDH1A1 | |
| SCHEMBL1798922 | 0.67 | ACHE (0.47) | TSHRTDP1ACHENPC1ALDH1A1 | |
| SCHEMBL80628 | 0.67 | ACHE (0.47) | TSHRTDP1ACHENPC1NPSR1 | |
| SCHEMBL1538886 | 0.65 | ACHE (0.44) | TSHRTDP1ACHEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501843-B1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-1501843-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6825295-B2 | COORDINATION POLYMERIZATION CATALYST | DOW GLOBAL TECHNOLOGIES INC. | 2004-11-30 | — | — | US | disclosed |
| WO-2003091265-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-6515155-B1 | Group 4 metal complexes of the constrained geometry type, catalysts derived therefrom and polymerization processes using the same, characterized by a nitrogen containing aliphatic or cycloaliphatic moiety that is substituted with one or more | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | disclosed |
| US-20030004286-A1 | Alkaryl-substituted Group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-01-02 | — | — | US | disclosed |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | KLOSIN JERZY (US) | 2002-11-07 | — | — | US | disclosed |
| EP-1253158-A1 | Substituted group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1242471-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042315-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | B2M, WEE2, WASF2 | TSHR 4005/4885TDP1 4787/4885ACHE 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.