Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624673 | 0.81 | S1PR1 (0.42) | CTSLCTSKDPP4CTSBS1PR1 | |
| SCHEMBL4554930 | 0.74 | CTSL (0.38) | CTSLCTSKCTSBCYP1A2S1PR1 | |
| SCHEMBL7242446 | 0.67 | CTSL (0.40) | SIGMAR1CTSLCTSKCTSBCYP1A2 | |
| SCHEMBL4153144 | 0.67 | CTSL (0.31) | CTSLCTSKPOLB | |
| SCHEMBL1966053 | 0.64 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL1375288 | 0.64 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL4080897 | 0.64 | — | — | |
| SCHEMBL6512644 | 0.63 | S1PR1 (0.46) | POLBMEN1MAPTKMT2AS1PR1 | |
| SCHEMBL31750308 | 0.63 | CTSL (0.38) | CTSLCTSKCTSB | |
| SCHEMBL4166319 | 0.62 | DPP7 (0.33) | DPP4DPP7DPP8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162969-B1 | use of dipeptidyl peptidase IV inhibitors fOR IMPROVING FERTILITY | FERRING BV (NL) | 2006-06-07 | — | — | EP | claimed |