Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512644 | 0.82 | S1PR1 (0.46) | S1PR1S1PR3S1PR5CHRNB2CHRNA7 | |
| SCHEMBL11644631 | 0.81 | ALDH1A1 (0.34) | S1PR1S1PR3S1PR5CHRNB2CHRNA7 | |
| SCHEMBL5696209 | 0.81 | SIGMAR1 (0.40) | S1PR1S1PR3S1PR5CTSLCTSK | |
| SCHEMBL6507955 | 0.76 | S1PR1 (0.40) | S1PR1S1PR3S1PR5CHRNB2CHRNA7 | |
| SCHEMBL4554930 | 0.75 | CTSL (0.38) | S1PR1S1PR3S1PR5CTSLCTSK | |
| SCHEMBL11647013 | 0.75 | — | — | |
| SCHEMBL13183150 | 0.73 | CTSL (0.38) | CTSLCTSKCTSB | |
| SCHEMBL292866 | 0.73 | S1PR1 (0.54) | S1PR1S1PR3S1PR5CHRNB2CHRNA7 | |
| SCHEMBL15481483 | 0.72 | S1PR1 (0.45) | S1PR1S1PR3S1PR5CHRNB2CHRNA7 | |
| SCHEMBL292865 | 0.72 | S1PR1 (0.45) | S1PR1S1PR3S1PR5CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109627088-A | A kind of Intelligent controlled release medicine fat particles agent of nitrile compounds containing aryl-pyrrolidine and pyridine insecticides | 河南好年景生物发展有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-105622598-B | Aryl-pyrrolidine nitrile compounds and preparation method and purposes and agricultural insecticide and pest control method for desinsection | 河南好年景生物发展有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-105622598-A | Arylpyrrole nitrile compound used for killing insects, preparation method and application thereof, agricultural insecticide and pest prevention method | HENAN HAONIANJING BIOLOGY DEV CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-1501796-A | Treatment of type 2 diabetes mellitus using inhibitors of dipeptidyl peptidase IV | ���ֹɷݹ�˾ | 2004-06-02 | — | — | CN | claimed |
| CN-109627088-A | A kind of Intelligent controlled release medicine fat particles agent of nitrile compounds containing aryl-pyrrolidine and pyridine insecticides | 河南好年景生物发展有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109627088-A | A kind of Intelligent controlled release medicine fat particles agent of nitrile compounds containing aryl-pyrrolidine and pyridine insecticides | 河南好年景生物发展有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109369498-A | A kind of method that microreactor continuously synthesizes the bromo- 2- rubigan -5- trifluoromethyl pyrpole -3- nitrile of 4- | 湖南海利常德农药化工有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109169668-A | 2- aryl substituted pyrroles class compound is killing the application in vesicle spiral shell drug | 江苏省血吸虫病防治研究所 | 2019-01-11 | — | — | CN | disclosed |
| CN-109006823-A | Application of the 2- aryl substituted pyrroles class compound in snail-killing medicine | 江苏省血吸虫病防治研究所 | 2018-12-18 | — | — | CN | disclosed |
| CN-109006824-A | 2- aryl substituted pyrroles class compound is killing the application in double navel spiral shell drugs | 江苏省血吸虫病防治研究所 | 2018-12-18 | — | — | CN | disclosed |
| CN-106083628-B | A kind of method for preparing p-chlorophenylglycine | 河北大学 | 2018-06-26 | — | — | CN | disclosed |
| CN-105622598-B | Aryl-pyrrolidine nitrile compounds and preparation method and purposes and agricultural insecticide and pest control method for desinsection | 河南好年景生物发展有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-1439634-A | Preparation of 2-aryl-5-(trifluoride) pyrrole-3-nitrile and its use and preparation of its intermediate thereof | JIANGSU PESTICIDE INST CO LTD (CN) | 2003-09-03 | — | — | CN | disclosed |
| CN-1066442-C | Manufacture of 4-aryl 1-2-perfluoroalkyl-3-oxazolin-5-one from arylglycine | AMERICAN CYANAMID CO (US) | 2001-05-30 | — | — | CN | disclosed |
| CN-1053661-C | Method for the preparation of 2-perflouoroalkyl-3-oxazolin-5-one | AMERICAN CYANAMID CO (US) | 2000-06-21 | — | — | CN | disclosed |
| CN-1170721-A | Ammonium oxazole and amino oxazolium intermediates, methods for preparation thereof and use therefor in manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | CN | disclosed |
| CN-1170718-A | Process for manufacture of 2-aryl-5-perfluoroalkylpyrrole derivatives and intermediates useful therefor | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | CN | disclosed |
| CN-1133836-A | Process for manufacture of insecticidal arylpyrrolwa via oxazole amine intermediates | AMERICAN CYANAMID CO (US) | 1996-10-23 | — | — | CN | disclosed |
| CN-1132749-A | Manufacture of 4-aryl 1-2-perfluoroalkyl-3-oxazolin-5-one from arylglycine | AMERICAN CYANAMID CO (US) | 1996-10-09 | — | — | CN | disclosed |
| CN-1107148-A | Method for the preparation of 2-perflouoroalkyl-3-oxazolin-5-one | AMERICAN CYANAMID CO (US) | 1995-08-23 | — | — | CN | disclosed |