Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624673 | 0.75 | S1PR1 (0.42) | CTSLCTSKCTSBS1PR1S1PR3 | |
| SCHEMBL5696209 | 0.74 | SIGMAR1 (0.40) | CTSLCTSKCTSBS1PR1S1PR3 | |
| SCHEMBL13183150 | 0.73 | CTSL (0.38) | CTSLCTSKCTSBCTSSCTSH | |
| SCHEMBL25764965 | 0.72 | CYP1A2 (0.32) | S1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL12535509 | 0.72 | CYP1A2 (0.58) | S1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL11647952 | 0.70 | S1PR1 (0.47) | S1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL14941314 | 0.70 | LMNA (0.36) | CYP1A2 | |
| SCHEMBL1103885 | 0.68 | GPR119 (0.48) | CTSLCTSKCTSBCTSSGPR119 | |
| SCHEMBL7242446 | 0.68 | CTSL (0.40) | CTSLCTSKCTSBCTSSCYP1A2 | |
| SCHEMBL7013626 | 0.68 | CTSL (0.40) | CTSLCTSKCTSBCTSSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | disclosed |