Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398350 | 0.91 | CES2 (0.58) | GAAHTTALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL1624304 | 0.89 | KMT2A (0.52) | GAAALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL13476677 | 0.88 | ALDH1A1 (0.49) | CA4GAAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9353461 | 0.86 | TDP1 (0.54) | ALDH1A1SMN1; SMN2LTA4HKDM4EHPGD | |
| SCHEMBL9353455 | 0.86 | TDP1 (0.54) | ALDH1A1SMN1; SMN2LTA4HKDM4EHPGD | |
| SCHEMBL27352197 | 0.86 | TDP1 (0.54) | ALDH1A1SMN1; SMN2LTA4HKDM4EHPGD | |
| SCHEMBL18073 | 0.86 | TDP1 (0.54) | ALDH1A1SMN1; SMN2LTA4HKDM4EHPGD | |
| SCHEMBL9241160 | 0.86 | TDP1 (0.54) | ALDH1A1SMN1; SMN2LTA4HKDM4EHPGD | |
| Anisole SCHEMBL5689479 | 0.85 | ELANE (0.66) | CA4GAAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL16675176 | 0.84 | CES2 (0.52) | GAAHTTALDH1A1SMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745254-B2 | Two-step and one-pot processes for preparation of aliphatic diisocyanates | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2017-08-29 | — | — | US | disclosed |
| CN-106349110-A | Two-stage method and one-pot synthesis method for preparing aliphatic diisocyanate | 大东树脂化学股份有限公司 | 2017-01-25 | — | — | CN | disclosed |
| US-20170015621-A1 | TWO-STEP AND ONE-POT PROCESSES FOR PREPARATION OF ALIPHATIC DIISOCYANATES | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2017-01-19 | — | — | US | disclosed |
| CN-106146832-A | Method for producing aliphatic amine dicarboxylic acid ester, aliphatic amine polycarboxylic acid ester and polyurea using diaryl carbonate | 大东树脂化学股份有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20160090351-A1 | INHIBITORS OF DEUBIQUITINATING PROTEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-31 | — | — | US | disclosed |
| US-20160090351-A1 | INHIBITORS OF DEUBIQUITINATING PROTEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-31 | — | — | US | disclosed |
| WO-2014172638-A2 | INHIBITORS OF DEUBIQUITINATING PROTEASES | BRANDEIS UNIVERSITY (US) | 2014-10-23 | — | — | WO | disclosed |
| EP-1412411-B1 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GEN ELECTRIC (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1118644-B1 | Hot melt printing ink | SIEGWERK DRUCKFARBEN AG (DE) | 2006-06-14 | — | — | EP | disclosed |
| EP-1412411-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6620902-B2 | Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing | GENERAL ELECTRIC COMPANY | 2003-09-16 | — | — | US | disclosed |
| US-20030088051-A1 | Process for preparing polycarbonate and apparatus for preparing polycarbonate | GENERAL ELECTRIC COMPANY | 2003-05-08 | — | — | US | disclosed |
| WO-2003008481-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-01-30 | — | — | WO | disclosed |
| EP-1118644-A2 | Hot melt printing ink | Siegwerk Druckfarben GmbH & Co. KG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-5523451-A | Process for the continuous preparation of aryl carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | disclosed |
| US-5362901-A | Process for the preparation of organic carbonates having at least one aromatic ester group | BAYER AKTIENGESELLSCHAFT (DE) | 1994-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090351-A1 | INHIBITORS OF DEUBIQUITINATING PROTEASES | USP1, USP2, USP18 | CA4 3407/4885GAA 328/4885HTT 2108/4885 |
| US-20170015621-A1 | TWO-STEP AND ONE-POT PROCESSES FOR PREPARATION OF ALIPHATIC DIISOCYANATES | PARG, CDIPT, CDS2 | CA4 1721/4885GAA 1378/4885HTT 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.