Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551296 | 0.85 | LMNA (0.50) | LMNAALDH1A1GAAPOLBKDM4E | |
| SCHEMBL4197298 | 0.81 | LMNA (0.56) | LMNAALDH1A1GAAPOLBTP53 | |
| SCHEMBL27338868 | 0.81 | LMNA (0.52) | LMNAALDH1A1GAAPOLBKDM4E | |
| Ammonia Solution, Strong SCHEMBL11408777 | 0.79 | LMNA (0.55) | LMNAALDH1A1GAAPOLBTP53 | |
| SCHEMBL5524122 | 0.78 | LMNA (0.53) | LMNAALDH1A1GAAPOLBTP53 | |
| SCHEMBL27524490 | 0.78 | LMNA (0.49) | LMNAALDH1A1GAAPOLBKDM4E | |
| SCHEMBL11408791 | 0.76 | ALDH1A1 (0.47) | LMNAALDH1A1GAAPOLBKDM4E | |
| SCHEMBL9064462 | 0.76 | TDP1 (0.49) | LMNAALDH1A1GAAPOLBKDM4E | |
| SCHEMBL9348267 | 0.76 | TDP1 (0.49) | LMNAALDH1A1GAAPOLBKDM4E | |
| SCHEMBL166122 | 0.75 | TDP1 (0.57) | LMNAALDH1A1GAAPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656201-A1 | ARSENIC-ADSORBING ION EXCHANGER | Lanxess Deutschland GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2004110623-A1 | ARSENIC-ADSORBING ION EXCHANGER | LANXESS DEUTSCHLAND GMBH (DE) | 2004-12-23 | — | — | WO | disclosed |