Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697210 | 0.82 | TSHR (0.48) | NPSR1CA12CA1CA2CA9 | |
| SCHEMBL5821176 | 0.82 | BCAT1 (0.44) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL1140105 | 0.68 | PNMT (0.41) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL11807178 | 0.68 | CYP2C19 (0.55) | CA1CA2KMT2ATSHRMAPK1 | |
| SCHEMBL15667939 | 0.67 | TDP1 (0.45) | NPSR1CA1CA2KMT2AMEN1 | |
| SCHEMBL9430743 | 0.66 | L3MBTL1 (0.49) | KMT2AMEN1PKM | |
| SCHEMBL1828000 | 0.65 | CA1 (0.35) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL1374138 | 0.65 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL167548 | 0.65 | SMN1; SMN2 (0.58) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL483344 | 0.64 | ALDH1A1 (0.62) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283556-A | Process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene | TOMS RIVER CHEMICAL CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |