Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583313 | 0.70 | LTA4H (0.46) | KMT2AKDM4EGLAMAPTALDH1A1 | |
| SCHEMBL11095075 | 0.69 | CA4 (0.34) | KMT2AALDH1A1LTA4HLMNA | |
| SCHEMBL10799799 | 0.68 | SLC6A4 (0.42) | KMT2AALDH1A1HPGDHTTLTA4H | |
| SCHEMBL22325826 | 0.66 | MAOA (0.38) | KMT2AKDM4EGLAMAPTALDH1A1 | |
| SCHEMBL22185236 | 0.66 | CA12 (0.39) | KMT2AKDM4EGLAMAPTALDH1A1 | |
| SCHEMBL14431354 | 0.66 | GABRA1 (0.44) | KMT2AMAPTHPGDTSHRLMNA | |
| SCHEMBL24713376 | 0.65 | ALDH1A1 (0.42) | KMT2AMAPTALDH1A1HPGDHTT | |
| SCHEMBL9102119 | 0.65 | LTA4H (0.35) | KMT2AKDM4EGLAMAPTALDH1A1 | |
| SCHEMBL6062443 | 0.64 | GABRA1 (0.53) | KMT2AKDM4EMAPTHPGDALOX12 | |
| SCHEMBL6619121 | 0.63 | LTA4H (0.46) | KMT2AALDH1A1HPGDHTTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-B1 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |