Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922836 | 0.86 | CA2 (0.55) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL8395286 | 0.79 | MAPT (0.58) | CA2CA9MEN1KMT2ARAB9A | |
| SCHEMBL2705170 | 0.78 | GAA (0.59) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31357262 | 0.77 | THRB (0.39) | CA2CA9CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4225554 | 0.77 | CA12 (0.53) | CA2CA9MEN1KMT2ACYP1A2 | |
| SCHEMBL196987 | 0.77 | CA2 (0.46) | CA2CA9RAB9AALDH1A1MAPT | |
| SCHEMBL7439011 | 0.77 | MEN1 (0.43) | CA2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7109290 | 0.77 | ALDH1A1 (0.47) | CA2CA9MEN1KMT2ARECQL | |
| SCHEMBL9172643 | 0.77 | LOXL2 (0.48) | CA2CA9MEN1KMT2ARAB9A | |
| SCHEMBL17373965 | 0.77 | CA2 (0.46) | CA2CA9CYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957263-B2 | Bromodomain inhibitors | ABBVIE INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160272630-A1 | Bromodomain Inhibitors | ABBVIE INC. (US) | 2016-09-22 | — | — | US | disclosed |
| EP-3013827-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014206345-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| EP-1569909-B1 | SUBSTITUTED PYRAZOLINE CARBOXANILIDES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2006-07-05 | — | — | EP | disclosed |
| US-20060100260-A1 | Substituted pyrazoline carboxanilides for use as pesticides | BAYER CROSCIENCE AG (DE) | 2006-05-11 | — | — | US | disclosed |
| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |
| US-5245071-A | Insecticides | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-09-14 | — | — | US | disclosed |
| US-5153316-A | Post and preemergence herbicides | DOWELANCO | 1992-10-06 | — | — | US | disclosed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
| US-4420619-A | Imidazole urea and amido compounds | CIBA-GEIGY CORPORATION (US) | 1983-12-13 | — | — | US | disclosed |
| EP-0004561-B1 | UREA AND AMIDE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICALS CONTAINING THEM AND THEIR USE FOR PREPARING PHARMACEUTICAL COMPOSITIONS | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |
| US-4292429-A | Imidazole urea and amido compounds | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0031965-A2 | Process for the preparation of tricyclic compounds, intermediates useful in said process, novel tricyclic compounds so prepared and the use thereof as odoriferous agents | Roure Bertrand Dupont Société Anonyme (FR) | 1981-07-15 | — | — | EP | disclosed |
| US-4166124-A | IMIDAZOLE OR PYRIMIDINE RINGS | U.S. PHILIPS CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| US-4146647-A | PHENYLAMIDOXIMES, HYPOTENSIVE AGENTS | LABORATOIRE L. LAFON (FR) | 1979-03-27 | — | — | US | disclosed |
| US-4110469-A | Insecticidal N-(2,6-dichlorobenzoyl)-N'-(4-cyanophenyl) urea | U.S. PHILIPS CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4013717-A | BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES | U.S. PHILIPS CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3989842-A | Certain substituted benzoyl urea insecticides | U.S. PHILIPS CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3933908-A | INSECTICIDE | U.S. PHILIPS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272630-A1 | Bromodomain Inhibitors | BRD4, BRDT, EP300 | CA2 4542/4885CA9 4427/4885MEN1 2984/4885 |
| US-20060100260-A1 | Substituted pyrazoline carboxanilides for use as pesticides | DDT, CHRM2, CHRM1 | CA2 1281/4885CA9 2954/4885MEN1 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.