Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL4629933 | 1.00 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL1163746 | 0.97 | FDPS (0.56) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL396638 | 0.97 | FDPS (0.56) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL7614882 | 0.97 | FDPS (0.56) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL2235358 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL3906363 | 0.94 | FDPS (0.62) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL4893670 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL22772236 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL29277658 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL28833809 | 0.94 | FDPS (0.62) | FDPSBLMTDP1SLC34A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106950095-A | A kind of method for reducing the interference of piarhemia pattern detection | 合肥迪安医学检验所有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-105925635-A | Production process of icariside II | 宁波旋光医药科技有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-110616243-A | Rhamnolipid fermentation medium and preparation method and application thereof | 深圳市仙湖植物园管理处 | 2019-12-27 | — | — | CN | disclosed |
| CN-108034973-A | The direct electroplating hole metallization solution and preparation method of a kind of printed circuit board (PCB) | 深圳市贝加电子材料有限公司 | 2018-05-15 | — | — | CN | disclosed |
| CN-107796896-A | A kind of assay method of furfural content in transformer oil | 广西电网有限责任公司电力科学研究院 | 2018-03-13 | — | — | CN | disclosed |
| CN-107058277-A | A kind of application of soybean protein and preparation method thereof and expression vector, primer | 深圳大学 | 2017-08-18 | — | — | CN | disclosed |
| EP-1670881-A1 | FUEL ADDITIVE WITH REDUCED EMISSION | Raisz, Ivan (HU) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023965-A1 | FUEL ADDITIVE WITH REDUCED EMISSION | RAISZ IVAN (HU) | 2005-03-17 | — | — | WO | disclosed |