Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL3906363 | 1.00 | FDPS (0.62) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL9491126 | 0.97 | FDPS (0.59) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL396638 | 0.97 | FDPS (0.56) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL1163746 | 0.97 | FDPS (0.56) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL11205119 | 0.97 | FDPS (0.67) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL10908279 | 0.97 | FDPS (0.67) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL2235358 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL4629933 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL22772236 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL5698120 | 0.94 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083287-A | A kind of direct sowing of rice dedicated fertilizer | 郎溪县飞鲤镇杨静粮食种植家庭农场 | 2016-11-09 | — | — | CN | disclosed |
| CN-106064969-A | A kind of method for the treatment of in accordance with local conditions preparation paddy rice-dedicated fertilizer | 郎溪县飞鲤镇杨静粮食种植家庭农场 | 2016-11-02 | — | — | CN | disclosed |
| CN-106045618-A | Method for preparing fertilizer special for wheat | 郎溪县飞鲤镇杨静粮食种植家庭农场 | 2016-10-26 | — | — | CN | disclosed |
| CN-106045672-A | Special fertilizer for direct seeding of lodging-resistant rice | 郎溪县飞鲤镇杨静粮食种植家庭农场 | 2016-10-26 | — | — | CN | disclosed |