Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL1163746 | 1.00 | FDPS (0.56) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL28833809 | 0.97 | FDPS (0.62) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL22772236 | 0.97 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL27604888 | 0.97 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL5698120 | 0.97 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL2235358 | 0.97 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL3906363 | 0.97 | FDPS (0.62) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL4629933 | 0.97 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL28169716 | 0.97 | FDPS (0.53) | FDPSBLMTDP1SLC34A1KDM4E | |
| Pyrophosphoric Acid SCHEMBL118122 | 0.97 | FDPS (0.60) | FDPSBLMTDP1SLC34A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026104902-A1 | COMPOSITIONS AND METHODS FOR INCREASING THE PALATABILITY OF DRY DOG FOOD | SOCIETE DES PRODUITS NESTLE SA (CH) | 2026-05-21 | — | — | WO | claimed |
| US-20260137104-A1 | COMPOSITIONS AND METHODS FOR INCREASING THE PALATABILITY OF DRY DOG FOOD | Société des Produits Nestlé S.A. (CH) | 2026-05-21 | — | — | US | claimed |
| CN-122031300-A | Plant cellulose abrasive, preparation method and application thereof, and toothpaste and dentifrice prepared from plant cellulose abrasive | 广州纳英化工有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4660286-A1 | DESCALING AGENT FOR REMOVING SCALE IN HOT WORKING OF METALS | Chemische Fabrik Budenheim KG (DE) | 2025-12-10 | — | — | EP | claimed |
| EP-4611098-A1 | SOLID ELECTROLYTE AND ELECTRODE FOR A SOLID-STATE BATTERY COMPRISING FUNCTIONAL FILLERS AND DISPERSING AGENTS, AND METHODS FOR PRODUCING THE SAME | SOLiTHOR (BE) | 2025-09-03 | — | — | EP | claimed |
| CN-119867155-A | DHA-containing children cheese sausage and preparation method thereof | 上海妙可蓝多生物技术研发有限公司 | 2025-04-25 | — | — | CN | claimed |
| EP-3065557-B2 | DRY PET FOOD COMPRISING A PALATABILITY ENHANCING COATING | MARS INC (US) | 2025-03-26 | — | — | EP | claimed |
| CN-119424257-A | Composition and application thereof, toothpaste and preparation method of toothpaste | 广州立白科技集团有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-20240374492-A1 | A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION | ISP INVESTMENTS LLC (US) | 2024-11-14 | — | — | US | claimed |
| CN-115999592-B | Naphtha catalytic reforming catalyst and preparation method thereof | 中国石油化工股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| WO-1999019443-A1 | MID-CHAIN BRANCHED SURFACTANTS WITH POTASSIUM IONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-22 | — | — | WO | claimed |
| EP-0881938-A4 | NOVEL METHODS AND APPARATUS FOR OSMOTIC DISTILLATION | RENTIERS MACHINERY PTY LTD (AU) | 1999-04-14 | — | — | EP | claimed |
| US-5855875-A | TELESCOPICALLY MULTICAVITIES DISPENSING CONTAINERS | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1999-01-05 | — | — | US | claimed |
| EP-0881938-A1 | NOVEL METHODS AND APPARATUS FOR OSMOTIC DISTILLATION | Rentiers Machinery Proprietary Ltd. (AU) | 1998-12-09 | — | — | EP | claimed |
| US-5824223-A | Methods and apparatus for osmotic distillation | RENTIERS MACHINERY PROPRIETARY LTD. (AU) | 1998-10-20 | — | — | US | claimed |
| US-5814303-A | PACKAGED IN A TELESCOPICALLY ARRANGED MULTI-CAVITY DISPENSING CONTAINER HAVING AT LEAST TWO CYLINDERS; PEROXIDE AND BAKING SODA ARE ACTIVE INGREDIENTS; UNIFORM DISPENSING BY INCORPORATING A POLYPHOSPHATE SALT TO ADJUST VISCOSITY | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOCPO, INC. (US) | 1998-09-29 | — | — | US | claimed |
| EP-0839517-A2 | Dental product | UNILEVER N.V. (NL) | 1998-05-06 | — | — | EP | claimed |
| EP-0309414-A2 | Chewing gum having antitartar activity | AVANTGARDE S.p.A. (IT) | 1989-03-29 | — | — | EP | claimed |
| US-4529701-A | Inorganic pyrophosphate containing compound | AMERICAN GENETICS INTERNATIONAL, INC. (US) | 1985-07-16 | — | — | US | claimed |
| US-3934049-A | ALKALI METAL PYROPHOSHATE AND CARBONATE, ALKALINE EARTH METAL ORTHO-PHOSPHATE, AND PREGELATINIZED STARCH OR GUMS | STAUFFER CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260137104-A1 | COMPOSITIONS AND METHODS FOR INCREASING THE PALATABILITY OF DRY DOG FOOD | PLCD1, PLCB3, PLCG2 | FDPS 611/4885BLM 4278/4885TDP1 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.