Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | BRAF | P15056 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744709 | 0.87 | TSHR (0.67) | PKMTDP1KMT2ARAB9AKDM4E | |
| SCHEMBL28676345 | 0.86 | MEN1 (0.72) | KMT2APOLBRAB9AKDM4EMEN1 | |
| SCHEMBL5420319 | 0.83 | KMT2A (0.90) | PKMTDP1KMT2APOLBRAB9A | |
| SCHEMBL14880379 | 0.82 | PKM (0.79) | PKMTDP1KMT2APOLBRAB9A | |
| SCHEMBL30151533 | 0.79 | RAB9A (1.00) | PKMTDP1KMT2APOLBRAB9A | |
| SCHEMBL11129936 | 0.79 | RAB9A (1.00) | PKMTDP1KMT2APOLBRAB9A | |
| SCHEMBL6352080 | 0.79 | ALDH1A1 (0.76) | PKMTDP1KMT2APOLBRAB9A | |
| SCHEMBL24074161 | 0.78 | TSHR (0.74) | PKMTDP1KMT2APOLBKDM4E | |
| SCHEMBL10990122 | 0.78 | MEN1 (0.61) | PKMTDP1KMT2APOLBRAB9A | |
| SCHEMBL10515711 | 0.78 | MEN1 (0.65) | PKMTDP1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687256-A1 | NOVEL PHENOXYACETAMIDE DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF DIPHENYLAMINES | MERCK PATENT GmbH (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051892-A1 | NOVEL PHENOXYACETAMIDE DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF DIPHENYLAMINES | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | disclosed |