Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698989 | 1.00 | KIF11 (0.41) | KIF11CES2CES1ORAI1ORAI2 | |
| SCHEMBL1350898 | 0.83 | TNKS (0.40) | KIF11CES2CES1ORAI1ORAI2 | |
| SCHEMBL19124264 | 0.82 | NR1H2 (0.44) | KIF11CES2CES1ORAI1ORAI2 | |
| SCHEMBL6491495 | 0.82 | RAB9A (0.42) | LMNAHTTALDH1A1 | |
| SCHEMBL19148416 | 0.82 | NR1H2 (0.44) | KIF11CES2CES1ORAI1ORAI2 | |
| SCHEMBL24032604 | 0.81 | LMNA (0.50) | KIF11LMNAALDH1A1TSHR | |
| SCHEMBL12765048 | 0.79 | TSHR (0.50) | LMNAHTTALDH1A1TSHR | |
| SCHEMBL14934282 | 0.79 | TSHR (0.50) | LMNAHTTALDH1A1TSHR | |
| SCHEMBL16174369 | 0.79 | TSHR (0.50) | LMNAHTTALDH1A1TSHR | |
| SCHEMBL31556506 | 0.79 | CES2 (0.43) | KIF11CES2CES1ORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673463-A1 | METHOD FOR TRANSFORMING EPOXY CARRIER OF TRIFLUOROMETHYL GROUPS | Rhodia Chimie (FR) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005038036-A1 | METHOD FOR TRANSFORMING EPOXY CARRIER OF TRIFLUOROMETHYL GROUPS | RHODIA CHIMIE (FR) | 2005-04-28 | — | — | WO | disclosed |