Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.34 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667061 | 0.84 | HSD11B1 (0.33) | HSD11B1SLC6A4MEN1KMT2ARCE1 | |
| SCHEMBL1759000 | 0.80 | EGFR (0.35) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL568314 | 0.80 | EGFR (0.35) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL391322 | 0.80 | EGFR (0.35) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL20597643 | 0.79 | HSD11B1 (0.37) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL1680560 | 0.74 | EGFR (0.39) | EGFRERBB2HSD11B1SLC6A4DRD2 | |
| SCHEMBL7775994 | 0.74 | KDM1A (0.38) | EGFRERBB2HSD11B1SLC6A4DRD2 | |
| SCHEMBL11614041 | 0.74 | KDM1A (0.38) | HSD11B1SLC6A4DRD2MEN1KMT2A | |
| SCHEMBL5248281 | 0.74 | KDM1A (0.38) | HSD11B1SLC6A4DRD2MEN1KMT2A | |
| SCHEMBL9985983 | 0.73 | EGFR (0.36) | EGFRERBB2SLC6A4DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447464-A | Method for producing optically active compound | 首日生物制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-111032047-B | Method for producing optically active compound | 多特疗法-1公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-111032047-A | Process for producing optically active compound | 千年制药公司 | 2020-04-17 | — | — | CN | disclosed |
| EP-1146037-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS | NIPPON SODA CO (JP) | 2006-06-21 | — | — | EP | disclosed |
| EP-1532094-A1 | METHOD FOR THE HYDROFORMYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS, ESPECIALLY OLEFINS, IN THE PRESENCE OF CYCLIC CARBONIC ACID ESTERS | Oxeno Olefinchemie GmbH (DE) | 2005-05-25 | — | — | EP | disclosed |
| US-6878663-B2 | Method for producing palladium complex compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2005-04-12 | — | — | US | disclosed |
| WO-2004020380-A1 | METHOD FOR THE HYDROFORMYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS, ESPECIALLY OLEFINS, IN THE PRESENCE OF CYCLIC CARBONIC ACID ESTERS | OXENO OLEFINCHEMIE GMBH (DE) | 2004-03-11 | — | — | WO | disclosed |
| US-20020111482-A1 | Method for producing palladium complex compound | CENTRAL GLASS COMPANY, LIMITED | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111482-A1 | Method for producing palladium complex compound | PDCD1LG2, CD274, PDCD1 | EGFR 217/4885ERBB2 201/4885ERBB3 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.