SCHEMBL5700517

SCHEMBL5700517

Cc1ccc([C]=O)c([C]=N)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 2/20 0.33
GRM5 P41594 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
THRB P10828 1/20 0.30
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5962213 0.86 CYP2A6 (0.39) CYP1A2CYP2A6MAOAMAOBTP53
SCHEMBL5700519 0.86 CYP2A6 (0.39) CYP1A2CYP2A6GRM5MAOAMAOB
SCHEMBL98000 0.75 TDP1 (0.42) CYP1A2CYP2A6MAOAMAOBTP53
SCHEMBL1314814 0.75 TDP1 (0.42) CYP1A2CYP2A6GRM5MAOAMAOB
SCHEMBL21409675 0.74 KDM4E (0.37) CYP3A4
SCHEMBL21409747 0.74 HSP90AA1 (0.32)
SCHEMBL5700336 0.74 VCAM1 (0.35) TP53CYP3A4ALOX15SMN1; SMN2TDP1
SCHEMBL8321394 0.71 TDP1 (0.52) CYP1A2CYP2A6TP53CYP3A4THRB
SCHEMBL21201424 0.71 NFE2L2 (0.36) CYP1A2CYP2A6MAOAMAOBTP53
SCHEMBL3083170 0.71 ALDH1A1 (0.35) CYP1A2CYP2A6MAOAMAOBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146037-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO (JP) 2006-06-21 EP disclosed
US-6410749-B1 REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND NIPPON SODA CO., LTD. (JP) 2002-06-25 US disclosed
EP-1146037-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO., LTD. (JP) 2001-10-17 EP disclosed