SCHEMBL5700519

SCHEMBL5700519

Cc1ccc([C]=N)c([C]=N)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.39
CYP1A2 P05177 3/20 0.39
TDP1 Q9NUW8 5/20 0.35
ACHE P22303 3/20 0.35
TP53 P04637 3/20 0.35
ALOX15 P16050 3/20 0.35
CYP3A4 P08684 1/20 0.35
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPA1 O75762 1/20 0.35
GRM5 P41594 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.31
NQO2 P16083 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5700517 0.86 CYP1A2 (0.33) CYP2A6CYP1A2TDP1TP53ALOX15
SCHEMBL3843168 0.68 CYP2A6 (0.39) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL1003862 0.68 ALDH1A1 (0.46) CYP2A6ALDH1A1MAOAMAOBKDM4E
SCHEMBL5962213 0.68 CYP2A6 (0.39) CYP2A6CYP1A2TDP1ACHETP53
P-Xylene SCHEMBL27930065 0.66 ACHE (0.67) CYP2A6CYP1A2TDP1ACHEALDH1A1
SCHEMBL3686045 0.65 TDP1 (0.46) CYP2A6CYP1A2TDP1ACHETP53
SCHEMBL188630 0.64 TSHR (0.35) CYP2A6CYP1A2CYP3A4SMN1; SMN2ALDH1A1
SCHEMBL4060179 0.64 AR (0.42) CYP2A6CYP1A2ALDH1A1MAOAMAOB
SCHEMBL10899005 0.63
M-Xylene SCHEMBL28007889 0.63 ACHE (0.75) CYP1A2TDP1ACHETP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146037-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO (JP) 2006-06-21 EP disclosed
US-6410749-B1 REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND NIPPON SODA CO., LTD. (JP) 2002-06-25 US disclosed
EP-1146037-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO., LTD. (JP) 2001-10-17 EP disclosed