SCHEMBL5700673

SCHEMBL5700673

CCC(c1cccc(F)c1)C1CCCN(C(=O)C(=O)C(C)(C)CC)C1C(=O)S

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 14/20 0.44
RIPK1 Q13546 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5700583 0.89 FKBP1A (0.53) FKBP1A
SCHEMBL5700670 0.83 FKBP1A (0.44) FKBP1A
SCHEMBL5700683 0.81 FKBP1A (0.44) FKBP1A
SCHEMBL5966055 0.75 FKBP1A (0.49) FKBP1A
SCHEMBL5966154 0.72 FKBP1A (0.45) FKBP1ARIPK1
SCHEMBL5275386 0.71 FKBP1A (0.41) FKBP1ARIPK1
SCHEMBL6049183 0.70 RIPK1 (0.44) FKBP1ARIPK1
SCHEMBL4681434 0.68 FKBP1A (0.55) FKBP1A
SCHEMBL5700677 0.68 FKBP1A (0.49) FKBP1A
SCHEMBL7803435 0.68 FKBP1A (0.52) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083873-B1 HETEROCYCLIC THIOESTER AND KETONE HAIR GROWTH COMPOSITIONS AND USES MGI GP INC (US) 2006-08-09 EP claimed