Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497055 | 0.84 | MAPT (0.45) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL8298418 | 0.84 | MAPT (0.45) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL5700957 | 0.82 | ALDH1A1 (0.64) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL13506383 | 0.81 | GABBR2 (0.50) | ALDH1A1MAPTRAB9AL3MBTL1CNR2 | |
| SCHEMBL6578974 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL8589119 | 0.81 | L3MBTL1 (0.61) | ALDH1A1RAB9AHTTL3MBTL1CNR2 | |
| SCHEMBL38660016 | 0.81 | MEN1 (0.49) | ALDH1A1MAPTRAB9AHTTL3MBTL1 | |
| SCHEMBL7995142 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTRAB9AL3MBTL1POLB | |
| SCHEMBL6321159 | 0.81 | L3MBTL1 (0.51) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL5700869 | 0.78 | KMT2A (0.44) | ALDH1A1F2F10PRSS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |