Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818128 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL14072103 | 0.86 | ESR1 (0.50) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL6819314 | 0.83 | TSHR (0.47) | ALDH1A1TSHRLMNAMAPTCYP3A4 | |
| SCHEMBL27429591 | 0.81 | L3MBTL1 (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL8887250 | 0.80 | LMNA (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL3617109 | 0.80 | LMNA (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL3612779 | 0.80 | LMNA (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL15012239 | 0.80 | LMNA (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL15012754 | 0.80 | LMNA (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 | |
| SCHEMBL8623494 | 0.80 | LMNA (0.59) | ALDH1A1TSHRLMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105775-B1 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INC (US) | 2006-09-06 | — | — | EP | disclosed |
| EP-1105775-A4 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INC (US) | 2005-04-13 | — | — | EP | disclosed |
| US-6517746-B1 | Polarizing material is a complex of (a) elemental iodine; (b) a hydrohalide acid or an ammonium, alkali metal or alkaline earth halide; (c) a pyrazine-2,5-dicarboxylic acid; and (d) a monoamide or monoester of a pyrazine-2,5-dicarboxylic acid | RESEARCH FRONTIERS INCORPORATED | 2003-02-11 | — | — | US | disclosed |
| EP-1105775-A1 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INCORPORATED (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000003178-A1 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INCORPORATED (US) | 2000-01-20 | — | — | WO | disclosed |