Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248353 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10PDE4DLMNAPKM | |
| SCHEMBL3906143 | 0.83 | MAOA (0.56) | PDE4DPKMMAOAMAOBSLC6A4 | |
| SCHEMBL2881040 | 0.79 | HSD17B10 (0.39) | ALDH1A1HSD17B10LMNAMAPTTDP1 | |
| SCHEMBL3894249 | 0.78 | POLB (0.43) | ALDH1A1HSD17B10LMNAPKMMAPT | |
| SCHEMBL22782303 | 0.75 | MAOA (0.57) | PDE4DLMNAPKMMAOAMAOB | |
| SCHEMBL21255995 | 0.74 | MAOA (0.66) | PDE4DLMNAPKMMAOAMAOB | |
| SCHEMBL6500345 | 0.72 | MAPT (0.51) | ALDH1A1HSD17B10LMNAPKMMAOB | |
| SCHEMBL3493523 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10LMNAMAPTTSHR | |
| SCHEMBL29837128 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10LMNAMAPTTSHR | |
| SCHEMBL7759862 | 0.70 | HSD17B10 (0.41) | ALDH1A1HSD17B10LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687279-A1 | 7- [4-(4-CHLOROBENZYLOXY) BENZENESULFONYL]-8-METHOXY-3-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINIUM MALEATE OR TOSYLATE AS ANTIPSYCHOTICS | GLAXO GROUP LIMITED (GB) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051916-A1 | 7-[4-(4-CHLOROBENZYLOXY) BENZENESULFONYL]-8-METHOXY-3-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINIUM MALEATE OR TOSYLATE AS ANTIPSYCHOTICS | GLAXO GROUP LIMITED (GB) | 2005-06-09 | — | — | WO | disclosed |