Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22056886 | 0.88 | TOP2A (0.51) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL5701316 | 0.88 | TOP2A (0.51) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL941093 | 0.79 | TOP2A (0.70) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL9319994 | 0.79 | TOP2A (0.70) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL941092 | 0.79 | TOP2A (0.70) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL17183613 | 0.79 | RAB9A (0.56) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL3087162 | 0.79 | TOP2A (0.49) | LMNAKDM4EHTTSMN1; SMN2TOP2A | |
| SCHEMBL800985 | 0.79 | AGTR1 (0.53) | LMNAKDM4ESMN1; SMN2TOP2ARAB9A | |
| SCHEMBL29402921 | 0.79 | AGTR1 (0.53) | LMNAKDM4ESMN1; SMN2TOP2ARAB9A | |
| SCHEMBL28494134 | 0.78 | TOP2A (0.68) | LMNAKDM4EHTTSMN1; SMN2TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377591-B1 | TUMOUR INHIBITING GALLIUM COMPOUNDS | FAUSTUS FORSCHUNGS CIE (DE) | 2006-06-28 | — | — | EP | disclosed |