Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRTN3 | P24158 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.48 |
| ▸ | KLK1 | P06870 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | KLK8 | O60259 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57116 | 0.83 | ATM (0.51) | PRTN3CTSLCTSSELANEKLK1 | |
| SCHEMBL56409 | 0.82 | KYNU (0.50) | PRTN3CTSLCTSSELANEKLK1 | |
| SCHEMBL56467 | 0.81 | TP53 (0.55) | PRTN3CTSLCTSSELANEKLK1 | |
| SCHEMBL9123479 | 0.81 | SIRT2 (0.55) | PRTN3CTSLCTSSSIRT2SIRT1 | |
| SCHEMBL57136 | 0.80 | KYNU (0.48) | PRTN3CTSLCTSSELANESIRT2 | |
| SCHEMBL21174074 | 0.80 | KYNU (0.59) | PRTN3CTSLCTSSELANESIRT2 | |
| SCHEMBL21174075 | 0.80 | KYNU (0.59) | PRTN3CTSLCTSSELANESIRT2 | |
| SCHEMBL21174135 | 0.80 | KYNU (0.59) | PRTN3CTSLCTSSELANESIRT2 | |
| SCHEMBL56936 | 0.80 | CASP1 (0.48) | PRTN3CTSLCTSSELANEKLK1 | |
| SCHEMBL56615 | 0.79 | CTSS (0.48) | PRTN3CTSLCTSSELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129557-B2 | Phosphonic acid diester derivative and method for producing thereof | Nagai, Kazuhiro (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | HIRATAKE, GOU (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | PPA1, G6PD, PHOSPHO1 | PRTN3 2011/4885CTSL 3139/4885CTSS 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.