Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329362 | 1.00 | LMNA (0.55) | LMNASMN1; SMN2RNASE1TYMSTK1 | |
| SCHEMBL24595722 | 0.92 | LMNA (0.55) | LMNASMN1; SMN2RNASE1TYMSTK1 | |
| SCHEMBL6852678 | 0.89 | LMNA (0.67) | LMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL16311910 | 0.89 | LMNA (0.57) | LMNASMN1; SMN2RNASE1TYMSTK1 | |
| SCHEMBL13026818 | 0.89 | LMNA (0.67) | LMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL6374113 | 0.89 | LMNA (0.67) | LMNASMN1; SMN2RNASE1TK1 | |
| SCHEMBL12969271 | 0.88 | RNASE1 (0.61) | RNASE1TK1ABCG2ABCB1 | |
| SCHEMBL4278968 | 0.88 | RNASE1 (0.61) | RNASE1TK1ABCG2ABCB1 | |
| SCHEMBL22143532 | 0.88 | RNASE1 (0.61) | RNASE1TK1ABCG2ABCB1 | |
| SCHEMBL4278972 | 0.88 | RNASE1 (0.61) | RNASE1TK1ABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57140796-A | — | — | None | — | — | JP | disclosed |
| EP-2601202-A1 | BONE-TARGETING BISPHOSPHONATE DUPLEX DRUGS | SCHOTT, Herbert (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012016994-A1 | BONE-TARGETING BISPHOSPHONATE DUPLEX DRUGS | SCHOTT HERBERT (DE) | 2012-02-09 | — | — | WO | disclosed |
| EP-0227844-B1 | ANTIVIRAL DRUG | TEIJIN LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-5013828-A | Fluorinating 2'-deoxyuridine with fluorine gas, fatty acid salt present, acylation with acid anhydride or halide | CENTRAL GLASS COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| US-4916121-A | PHOSPHORYLASE INHIBITOR | TEIJIN LIMITED (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0202056-B1 | ANTITUMOR AGENT | TEIJIN LIMITED (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0202056-A1 | Antitumor agent | TEIJIN LIMITED (JP) | 1986-11-20 | — | — | EP | disclosed |
| JP-S57140796-A | 2'-DEOXY-5-FLUOROURIDINE DERIVATIVE AND ITS PREPARATION | FUNAI CORP | 1982-08-31 | — | — | JP | disclosed |
| EP-0009882-A1 | 2'-Deoxy-5-fluorouridine derivatives, a process for producing the same and antitumor agents comprising the same | FUNAI PHARMACEUTICAL IND., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |