Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14472219 | 0.86 | SMN1; SMN2 (0.45) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL6965451 | 0.82 | SMN1; SMN2 (0.50) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| Benzene SCHEMBL27466605 | 0.81 | ALDH1A1 (0.48) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL6965290 | 0.81 | ALDH1A1 (0.48) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL6962159 | 0.80 | L3MBTL1 (0.40) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL7628961 | 0.79 | MAPT (0.44) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL8594445 | 0.79 | GRM1 (0.37) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL6962164 | 0.75 | MAPT (0.35) | GAASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL6652808 | 0.75 | RBP4 (0.57) | GAAMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL7621072 | 0.74 | PKM (0.42) | SMN1; SMN2MAPTPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |