Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702238 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2RARGRXRAPPARG | |
| SCHEMBL2769622 | 0.87 | FKBP1A (0.37) | ALDH1A1SMN1; SMN2RARGRXRAPPARG | |
| SCHEMBL7873447 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2RXRARAB9ANPSR1 | |
| SCHEMBL7866010 | 0.70 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPSR1POLB | |
| SCHEMBL73359 | 0.69 | HSD17B10 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPSR1NPC1 | |
| SCHEMBL1631708 | 0.69 | HSD17B10 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPSR1NPC1 | |
| SCHEMBL73360 | 0.69 | HSD17B10 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPSR1NPC1 | |
| SCHEMBL7871674 | 0.68 | SMN1; SMN2 (0.82) | ALDH1A1SMN1; SMN2RAB9ANPSR1POLB | |
| SCHEMBL17092984 | 0.68 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2RAB9ANPSR1POLB | |
| SCHEMBL3292544 | 0.67 | VCAM1 (0.39) | RARGRXRAPPARGELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |