Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875487 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNARIPK1 | |
| SCHEMBL5702080 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL5702238 | 0.78 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL73360 | 0.77 | HSD17B10 (0.56) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL73359 | 0.77 | HSD17B10 (0.56) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL1631708 | 0.77 | HSD17B10 (0.56) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL7866287 | 0.72 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL7877738 | 0.71 | RAB9A (0.42) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL7873464 | 0.71 | RAB9A (0.42) | ALDH1A1SMN1; SMN2HSD17B10RAB9ALMNA | |
| SCHEMBL1788433 | 0.69 | GABRA1 (0.44) | SMN1; SMN2HSD17B10CYP2C19ELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313315-B1 | RESOLUTION; ENANTIOMORPHIC PURIFICATION; CRYSTALLIZATION IN SOLVENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1057810-A1 | Method for producing n-protected-azetidine-2-carboxylic acids | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-12-06 | — | — | EP | disclosed |