Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924350 | 0.83 | MAOB (0.50) | MAOBMAOAL3MBTL1BCHENR4A2 | |
| SCHEMBL14638496 | 0.81 | MAPK1 (0.45) | MEN1KMT2AGAAMCL1MAPT | |
| SCHEMBL197017 | 0.78 | LMNA (0.72) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL28866549 | 0.78 | MAOB (0.49) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL6350969 | 0.78 | L3MBTL1 (0.63) | SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL3364770 | 0.78 | NPC1 (0.50) | RAB9ANPC1XDHGSTP1MCL1 | |
| SCHEMBL6256087 | 0.77 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL12473775 | 0.77 | MAOB (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL27743534 | 0.77 | CYP1A2 (0.61) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL23483029 | 0.77 | LMNA (0.69) | RAB9ASMN1; SMN2MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476252-B | Pyrazolyl guanidine F1F 0-ATPase inhibitors and therapeutic uses thereof | 莱斯拉公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2601192-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012018909-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-09 | — | — | WO | disclosed |