Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452344 | 0.91 | TLR9 (0.51) | MAOBKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL12473775 | 0.85 | MAOB (0.48) | MAOBMAOATOP1ALOX5NSD2 | |
| SCHEMBL28129013 | 0.84 | BRD4 (0.54) | L3MBTL1MAPTMAPK1TDP1TLR9 | |
| SCHEMBL6448897 | 0.80 | MAOB (0.48) | MAOBTLR9TLR7 | |
| SCHEMBL3103763 | 0.80 | L3MBTL1 (0.44) | PPARGL3MBTL1MPO | |
| SCHEMBL570256 | 0.78 | RAB9A (0.56) | MAOBMAOAL3MBTL1MAPTGSTP1 | |
| SCHEMBL18995816 | 0.77 | GSTP1 (0.58) | MAOBMAOATOP1ALOX5KDM4E | |
| SCHEMBL23924350 | 0.77 | MAOB (0.50) | MAOBMAOAALOX5NSD2ABL1 | |
| SCHEMBL7910960 | 0.77 | ALPL (0.59) | MAOBMAOAKDM4EMAPTHSP90AA1 | |
| SCHEMBL6028879 | 0.77 | PTGER1 (0.53) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929271-A | Tyrosinase inhibitor and preparation method thereof and purposes | 中国药科大学 | 2018-12-04 | — | — | CN | disclosed |