Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475416 | 0.93 | NPC1 (0.36) | NPC1POLBMAPTRAB9APRKCI | |
| SCHEMBL5475423 | 0.86 | KIF11 (0.33) | NPC1POLBMAPTRAB9APRKCI | |
| SCHEMBL5478505 | 0.79 | PRKCI (0.31) | PRKCI | |
| SCHEMBL20726532 | 0.78 | GAA (0.39) | NPC1POLBMAPTRAB9ASIGMAR1 | |
| SCHEMBL5477823 | 0.78 | AKR1C3 (0.39) | POLBMAPT | |
| SCHEMBL5477711 | 0.77 | PRKCI (0.31) | PRKCI | |
| SCHEMBL5084688 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL25851108 | 0.74 | SIGMAR1 (0.43) | POLBMAPTRAB9ASIGMAR1HTR6 | |
| SCHEMBL5478995 | 0.72 | AKR1C3 (0.43) | POLBMAPT | |
| SCHEMBL14583072 | 0.72 | AKR1C3 (0.40) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1681284-A1 | AROMATIC POLYAMINE DERIVATIVE | Daicel Chemical Industries, Ltd. (JP) | 2006-07-19 | — | — | EP | disclosed |