Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963579 | 0.82 | HTR6 (0.56) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL5349810 | 0.81 | MAOB (0.49) | MAPTKMT2AMEN1ALDH1A1PIN1 | |
| SCHEMBL18988345 | 0.80 | MERTK (0.54) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5344266 | 0.80 | MAOB (0.50) | MAPTKMT2AMEN1ALDH1A1PIN1 | |
| SCHEMBL1339905 | 0.79 | L3MBTL1 (0.64) | MAPTKMT2AMEN1MAPK1RECQL | |
| SCHEMBL30668812 | 0.79 | L3MBTL1 (0.64) | MAPTKMT2AMEN1MAPK1RECQL | |
| SCHEMBL1298266 | 0.79 | MERTK (0.52) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL7569094 | 0.79 | MAPT (0.58) | MAPTKMT2AMEN1MAPK1RECQL | |
| SCHEMBL6230766 | 0.76 | ALDH1A1 (0.56) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27708859 | 0.76 | MAPT (0.64) | MAPTKMT2AMEN1MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994100-B1 | 3-ANILINO-2-CYCLOALKENONE DERIVATES | NIKKEN CHEMICALS CO LTD (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6235736-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0994100-A1 | 3-ANILINO-2-CYCLOALKENONE DERIVATES | Nikken Chemicals Company, Limited (JP) | 2000-04-19 | — | — | EP | disclosed |