Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748666 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL702232 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL15065366 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL1125718 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTHSD17B10LMNAERN1 | |
| SCHEMBL8393465 | 0.78 | LMNA (0.73) | ALDH1A1KMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL20346747 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| 1-Methoxy-3-Ethoxybenzene SCHEMBL1068417 | 0.77 | CYP3A4 (0.61) | ALDH1A1MAPK1MEN1KMT2ATP53 | |
| SCHEMBL24629095 | 0.77 | ERN1 (0.59) | ALDH1A1MAPTERN1KDM4ETDP1 | |
| SCHEMBL29793253 | 0.77 | ERN1 (0.59) | ALDH1A1MAPTERN1KDM4ETDP1 | |
| SCHEMBL5704536 | 0.76 | MAPT (0.60) | ALDH1A1MAPK1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933366-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6235739-B1 | ANTIINFLAMMATORY AGENTS; ANTIHISTAMINES; SKIN DISORDERS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0933366-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-08-04 | — | — | EP | disclosed |