Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 4/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704599 | 1.00 | EPHX1 (0.45) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL6556276 | 0.81 | EPHX1 (0.48) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL10622532 | 0.81 | EPHX1 (0.48) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| Hydrochloric Acid SCHEMBL5711578 | 0.80 | EPHX1 (0.47) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL7275924 | 0.77 | KDM4E (0.49) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL27345872 | 0.77 | SLC15A1 (0.44) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL7337442 | 0.77 | KDM4E (0.49) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL7412831 | 0.76 | SLC15A1 (0.50) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL6351074 | 0.76 | SLC15A1 (0.43) | EPHX1SLC15A1LAP3ANPEPCSNK1E | |
| SCHEMBL7412834 | 0.76 | SLC15A1 (0.50) | EPHX1SLC15A1LAP3ANPEPCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243576-B1 | PROCESSES FOR PRODUCING (AMINOMETHYL)TRIFLUOROMETHYLCARBINOL DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-6646150-B1 | Reacting 1,3-oxazolidin-5-one derivative with trialkyl-(trifluoromethyl)silane; removing trialkylsilyl group; reductive decyclization | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1243576-A1 | PROCESSES FOR PRODUCING (AMINOMETHYL)TRIFLUOROCARBINOL DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |