Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 6/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412834 | 1.00 | SLC15A1 (0.50) | SLC15A1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL7348243 | 0.84 | SLC15A1 (0.46) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6556276 | 0.82 | EPHX1 (0.48) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL10622532 | 0.82 | EPHX1 (0.48) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6558174 | 0.82 | RIPK1 (0.46) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7279403 | 0.82 | CTRB1 (0.45) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7279408 | 0.82 | CTRB1 (0.45) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6558171 | 0.82 | RIPK1 (0.46) | SLC15A1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL7348250 | 0.82 | LAP3 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL6556117 | 0.81 | CTRB1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256677-A | Enzyme inhibitor for treating acquired immune deficiency syndrome | ABBOTT LABORATORIES (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1992017176-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5151438-A | Enzyme inhibitors for treatment of aids | ABBOTT LABORATORIES (US) | 1992-09-29 | — | — | US | disclosed |