SCHEMBL635759

SCHEMBL635759

Cc1c(N)cccc1CO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.56
TSHR P16473 3/20 0.56
PIK3CA P42336 1/20 0.56
PDCD1 Q15116 3/20 0.53
CD274 Q9NZQ7 3/20 0.53
ALDH1A1 P00352 4/20 0.46
ESR1 P03372 1/20 0.44
KCNH2 Q12809 1/20 0.44
HPGD P15428 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CD44 P16070 1/20 0.39
APOBEC3G Q9HC16 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
KDM4E B2RXH2 1/20 0.35
KEAP1 Q14145 1/20 0.34
GABRA1 P14867 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10983053 0.98 CYP3A4 (0.54) CYP3A4TSHRPIK3CAPDCD1CD274
SCHEMBL27588386 0.89 CD44 (0.50) CYP3A4TSHRPIK3CAPDCD1CD274
SCHEMBL27606043 0.84 ALDH1A1 (0.47) CYP3A4TSHRPIK3CAPDCD1CD274
SCHEMBL6424004 0.83 PDCD1 (0.64) PDCD1CD274ESR1APOBEC3GCYP1A2
SCHEMBL3341757 0.83 CYP3A4 (0.52) CYP3A4TSHRPIK3CAPDCD1CD274
SCHEMBL840872 0.81 CYP3A4 (0.62) CYP3A4TSHRPIK3CAPDCD1CD274
SCHEMBL5929976 0.79 CYP3A4 (0.59) CYP3A4TSHRPIK3CAALDH1A1ESR1
SCHEMBL7406902 0.79 CYP3A4 (0.59) CYP3A4TSHRPIK3CAALDH1A1ESR1
SCHEMBL25259982 0.77 CYP3A4 (0.56) CYP3A4TSHRPIK3CAPDCD1CD274
SCHEMBL14115801 0.77 PDCD1 (0.53) TSHRPDCD1CD274APOBEC3GCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911795-B1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2025-10-01 EP claimed
CN-113646479-B Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2023-06-13 CN claimed
US-20220120031-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2022-04-21 US claimed
EP-3911795-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP Investments LLC (US) 2021-11-24 EP claimed
CN-113646479-A Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2021-11-12 CN claimed
EP-3565523-B1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS HERCULES LLC (US) 2021-09-08 EP claimed
CN-112621013-B Soldering tin bar special for solar photovoltaic solder strip and preparation method thereof 常州福伦特无铅焊料有限公司 2021-07-20 CN claimed
CN-112621013-A Soldering tin bar special for solar photovoltaic solder strip and preparation method thereof 常州福伦特无铅焊料有限公司 2021-04-09 CN claimed
WO-2020150384-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2020-07-23 WO claimed
EP-3565523-A1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS Hercules LLC (US) 2019-11-13 EP claimed
EP-2486115-B1 ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF FRAUNHOFER GES FORSCHUNG (DE) 2015-05-20 EP claimed
US-8288552-B2 Dihydropyridone amidesas P2X7 modulators ROCHE PALO ALTO LLC (US) 2012-10-16 US claimed
US-7547713-B2 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives GU LIANQUAN 2009-06-16 US claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
US-20060111405-A1 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives GU LIANQUAN 2006-05-25 US claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
US-6509393-B2 Phase change inks XEROX CORPORATION 2003-01-21 US claimed
US-20020137816-A1 Phase change inks XEROX CORPORATION 2002-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111405-A1 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives PTGS2, PTGES2, PTGES CYP3A4 32/4885TSHR 4772/4885PIK3CA 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.