Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705117 | 0.87 | LMNA (0.48) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL27861809 | 0.83 | ALDH1A1 (0.40) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL7191106 | 0.83 | CA12 (0.55) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL10905028 | 0.80 | SMN1; SMN2 (0.38) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL995336 | 0.79 | CA12 (0.46) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL31126854 | 0.79 | TSHR (0.62) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL7185633 | 0.79 | TSHR (0.49) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL9742579 | 0.79 | TSHR (0.62) | LMNATSHRALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL11570035 | 0.78 | SIGMAR1 (0.56) | TSHRALDH1A1POLBHPGDKDM4E | |
| SCHEMBL27541653 | 0.78 | TSHR (0.47) | LMNATSHRALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-6992214-B2 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030162995-A1 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES LLC | 2003-08-28 | — | — | US | disclosed |
| EP-1255728-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | Enichem S.p.A. (IT) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056977-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | ENICHEM S.P.A. (IT) | 2001-08-09 | — | — | WO | disclosed |