Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705166 | 0.87 | LMNA (0.42) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL995321 | 0.84 | LMNA (0.59) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL442790 | 0.77 | CHRNB2 (0.59) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| Benzene SCHEMBL1720409 | 0.77 | CHRNB2 (0.59) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL30541729 | 0.76 | LMNA (0.57) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL30679483 | 0.76 | ROCK2 (0.42) | LMNATSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL27861809 | 0.75 | ALDH1A1 (0.40) | LMNATSHRSMN1; SMN2CTDSP1KMT2A | |
| SCHEMBL7191106 | 0.75 | CA12 (0.55) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL9136344 | 0.74 | LMNA (0.62) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL8866817 | 0.74 | CYP4F2 (0.57) | LMNATSHRSMN1; SMN2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | claimed |
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-6992214-B2 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030162995-A1 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES LLC | 2003-08-28 | — | — | US | disclosed |