SCHEMBL5706149

SCHEMBL5706149

CC(C)(C)Oc1ccc(C(=O)Oc2ccccc2Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
PTK2B Q14289 1/20 0.43
NPC1 O15118 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
AHR P35869 1/20 0.43
RAB9A P51151 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HPGD P15428 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705968 0.86 MAPT (0.47) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706105 0.84 ELANE (0.41) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706251 0.83 L3MBTL1 (0.58) KMT2AMAPTL3MBTL1TDP1NPC1
SCHEMBL5706010 0.82 NPSR1 (0.59) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706082 0.80 SLC6A3 (0.68) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706048 0.80 SLC6A3 (0.58) KMT2AMAPTL3MBTL1TDP1PTK2B
SCHEMBL5705949 0.80 MAPT (0.63) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706143 0.80 ESR1 (0.56) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706060 0.79 NPSR1 (0.50) KMT2AMEN1MAPTL3MBTL1TDP1
SCHEMBL5706089 0.79 L3MBTL1 (0.55) KMT2AMEN1MAPTL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed