Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508228 | 0.79 | JAK1 (0.36) | JAK1GRM5 | |
| SCHEMBL4518143 | 0.78 | JAK1 (0.36) | JAK1 | |
| SCHEMBL5706343 | 0.75 | DPP4 (0.46) | — | |
| SCHEMBL24054526 | 0.70 | ACHE (0.42) | — | |
| SCHEMBL4513979 | 0.69 | FFAR1 (0.57) | — | |
| SCHEMBL4513984 | 0.69 | FFAR1 (0.57) | — | |
| SCHEMBL28783783 | 0.68 | HTR3E (0.47) | — | |
| SCHEMBL4365727 | 0.68 | HTR2A (0.40) | — | |
| SCHEMBL24054689 | 0.68 | CYP3A4 (0.41) | — | |
| SCHEMBL1419786 | 0.68 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696899-A1 | METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B | ALLERGAN, INC. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058301-A1 | METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B | ALLERGAN, INC. (US) | 2005-06-30 | — | — | WO | disclosed |