Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.51 |
| ▸ | ITGAL | P20701 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707133 | 1.00 | PLA2G4A (0.59) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL30641924 | 1.00 | PLA2G4A (0.59) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL832790 | 0.88 | MAPT (0.67) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL832791 | 0.88 | MAPT (0.67) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL2264118 | 0.83 | KDM4E (0.62) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL2264126 | 0.83 | KDM4E (0.62) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL3608483 | 0.81 | PLA2G4A (0.52) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL3608478 | 0.81 | PLA2G4A (0.52) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL11249530 | 0.81 | PLA2G4A (0.52) | PLA2G4AMAPTRAB9ARECQLMITF | |
| SCHEMBL8965252 | 0.80 | MAPT (0.81) | MAPTRAB9ARECQLMITFNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-117024371-A | Compound with function of reversing PD-1 drug resistance and application thereof | 中国人民解放军海军军医大学 | 2023-11-10 | — | — | CN | disclosed |
| EP-1718628-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Active Biotech AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| US-20050192289-A1 | Novel cinnamic amides | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | US | disclosed |
| WO-2005080362-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192289-A1 | Novel cinnamic amides | NFATC1, H1-5, HDAC1 | PLA2G4A 3114/4885MAPT 3799/4885RAB9A 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.