Sugi Predict

Sugi Predict / Compounds / SCHEMBL832791

SCHEMBL832791

SCHEMBL832791

O=C(O)C=Cc1ccc(Cl)c([N+](=O)[O-])c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.67
▸ RECQL P46063 2/20 0.67
▸ NPSR1 Q6W5P4 2/20 0.67
▸ MITF O75030 1/20 0.67
▸ RAB9A P51151 1/20 0.67
▸ PLA2G4A P47712 1/20 0.62
▸ VCAM1 P19320 3/20 0.61
▸ LMNA P02545 3/20 0.60
▸ HSP90AA1 P07900 1/20 0.60
▸ MEN1 O00255 6/20 0.57
▸ KMT2A Q03164 6/20 0.57
▸ POLB P06746 3/20 0.57
▸ TDP1 Q9NUW8 2/20 0.57
▸ HPGD P15428 1/20 0.57
▸ USP2 O75604 1/20 0.55
▸ MCL1 Q07820 1/20 0.55
▸ CTDSP1 Q9GZU7 1/20 0.55
▸ HTT P42858 2/20 0.53
▸ NPC1 O15118 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL832790 1.00 MAPT (0.67) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL5707129 0.88 PLA2G4A (0.59) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL5707133 0.88 PLA2G4A (0.59) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL30641924 0.88 PLA2G4A (0.59) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL11799189 0.86 MAPT (0.65) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL5829886 0.86 MAPT (0.65) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL8141148 0.86 MAPT (0.65) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL11799184 0.86 MAPT (0.65) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL2785447 0.83 ALDH5A1 (0.63) MAPTRECQLNPSR1MITFRAB9A
SCHEMBL10780080 0.83 MAPT (0.64) MAPTRECQLNPSR1MITFRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 — — US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 — — US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 — — US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 — — US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 — — WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 — — US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 — — US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 — — US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 — — US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 — — US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 — — US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 — — US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 — — US claimed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 — — US disclosed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP disclosed
EP-0912567-A1 CARBOLINE DERIVATIVES ICOS CORPORATION (US) 1999-05-06 — — EP disclosed
WO-1997043287-A1 CARBOLINE DERIVATIVES ICOS CORPORATION (US) 1997-11-20 — — WO disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS MAPT 2153/4885RECQL 2533/4885NPSR1 3502/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC MAPT 2945/4885RECQL 4526/4885NPSR1 3475/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS MAPT 2153/4885RECQL 2533/4885NPSR1 3502/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 MAPT 4074/4885RECQL 424/4885NPSR1 2989/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 MAPT 539/4885RECQL 1010/4885NPSR1 3033/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS MAPT 2153/4885RECQL 2533/4885NPSR1 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.