Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486859 | 1.00 | RAB9A (0.53) | RAB9AKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL10625694 | 1.00 | RAB9A (0.53) | RAB9AKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL77732 | 0.82 | MEN1 (0.63) | KMT2AMAPTMEN1NPSR1AKR1C3 | |
| SCHEMBL6064517 | 0.81 | ALDH1A1 (0.50) | KMT2AMAPTNPSR1ALDH1A1NFKB1 | |
| SCHEMBL5747001 | 0.80 | MEN1 (0.72) | RAB9AKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL4803624 | 0.80 | MEN1 (0.72) | RAB9AKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL1221498 | 0.80 | MEN1 (0.52) | KMT2AMAPTMEN1NPSR1ALDH1A1 | |
| SCHEMBL6065568 | 0.80 | HSD17B3 (0.46) | RAB9AKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL11007893 | 0.79 | AKR1C3 (0.59) | RAB9AKMT2AMAPTMEN1NPSR1 | |
| SCHEMBL18264401 | 0.79 | AKR1C3 (0.59) | RAB9AKMT2AMAPTMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718628-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Active Biotech AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| US-7084281-B2 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-08-01 | — | — | US | disclosed |
| WO-2005080362-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | WO | disclosed |
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2004-07-22 | — | — | US | disclosed |
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143125-A1 | Synthesis of dihalohydrins and tri- and tetra-substituted olefins | TALDO1, HDHD5, TKT | RAB9A 4146/4885KMT2A 2083/4885MAPT 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.